It’s impossible to predict the outcome or full impact of the North Korean attack on its neighbor, so uncertainty hung like a cloud over trading last week, and we all know how Wall Street feels about that. However, not only did stocks have a modest day down on Friday but they ended the day with a small rally. That's a good sign for bulls.
The S&P 500 support at 1174, and the 50-day moving averages of the major indices held. That is an encouragement to the bulls, and the fact that we got through the holiday week with little damage, we may even launch into December with a meaningful rally.
Sunday, November 28, 2010
Friday, November 26, 2010
Vitamin E Tocotrienols Show Immune-Boosting Potential
Daily supplements rich in vitamin E tocotrienols may boost the immune response and immune function in healthy women following a vaccination.
According to findings published in the European Journal of Clinical Nutrition, women who received daily supplements of a palm tocotrienol complex for one month prior to a single tetanus toxoid (TT) vaccine experienced improvements in their immune response, compared with women who received placebo prior to the vaccine.
Tocotrienols are a form of vitamin E that have traditionally been in the shadow of the more popular vitamin E form—tocopherols.
Overall, there are eight forms of vitamin E: four tocopherols (alpha, beta, gamma, delta) and four tocotrienols (alpha, beta, gamma, delta). Alpha-tocopherol (alpha-Toc) is the main source found in supplements and in the European diet, while gamma-tocopherol (gamma-Toc) is the most common form in the American diet.
Tocotrienols (TCT) are only minor components in plants, although several sources with relatively high levels include palm oil, cereal grains and rice bran.
To test the effects of the tocotrienol-rich palm fraction on immune function, Malaysia-based scientists recruited 108 healthy non-smoking women aged between 18 and 25 years. The women were randomly split into two groups: One group received 400 mg of the palm tocotrienol complex per day, and the other group received placebo (400 mg per day of soy oil), each for two months.
Blood samples were analyzed at the start of the study, and again after 28 and 56 days. After 28 days of supplementation all of the participants received a single shot of tetanus toxoid vaccine.
Results showed significant increases in levels of the anti-TT antibody, interferon (IFN)-gamma and interleukin (IL)-4 in the tocotrienol group, compared with placebo.
“This study provides evidence that daily supplementation of 400 mg tocotrienol-rich fraction can have a beneficial role in enhancing the immune response of healthy subjects following an immunogenic challenge such as vaccination,” stated the researchers.
Furthermore, blood levels of tocotrienols increased, compared with placebo, with the greatest increases in alpha-T3, followed by gamma-T3 and delta-T3.
According to findings published in the European Journal of Clinical Nutrition, women who received daily supplements of a palm tocotrienol complex for one month prior to a single tetanus toxoid (TT) vaccine experienced improvements in their immune response, compared with women who received placebo prior to the vaccine.
Tocotrienols are a form of vitamin E that have traditionally been in the shadow of the more popular vitamin E form—tocopherols.
Overall, there are eight forms of vitamin E: four tocopherols (alpha, beta, gamma, delta) and four tocotrienols (alpha, beta, gamma, delta). Alpha-tocopherol (alpha-Toc) is the main source found in supplements and in the European diet, while gamma-tocopherol (gamma-Toc) is the most common form in the American diet.
Tocotrienols (TCT) are only minor components in plants, although several sources with relatively high levels include palm oil, cereal grains and rice bran.
To test the effects of the tocotrienol-rich palm fraction on immune function, Malaysia-based scientists recruited 108 healthy non-smoking women aged between 18 and 25 years. The women were randomly split into two groups: One group received 400 mg of the palm tocotrienol complex per day, and the other group received placebo (400 mg per day of soy oil), each for two months.
Blood samples were analyzed at the start of the study, and again after 28 and 56 days. After 28 days of supplementation all of the participants received a single shot of tetanus toxoid vaccine.
Results showed significant increases in levels of the anti-TT antibody, interferon (IFN)-gamma and interleukin (IL)-4 in the tocotrienol group, compared with placebo.
“This study provides evidence that daily supplementation of 400 mg tocotrienol-rich fraction can have a beneficial role in enhancing the immune response of healthy subjects following an immunogenic challenge such as vaccination,” stated the researchers.
Furthermore, blood levels of tocotrienols increased, compared with placebo, with the greatest increases in alpha-T3, followed by gamma-T3 and delta-T3.
Wednesday, November 24, 2010
Antioxidant Alpha-Carotene
High blood levels of the antioxidant alpha-carotene appear to be associated with a reduced risk of dying over a 14-year period, according to a report posted online November 22 that will be published in the March 28 print issue of Archives of Internal Medicine.
Oxygen-related damage to DNA, proteins and fats may play a role in the development of chronic diseases like heart disease and cancer, according to background information in the article.
Carotenoids -- including beta-carotene, alpha-carotene and lycopene -- are produced by plants and microorganisms and act as antioxidants, counteracting this damage. Carotenoids in the human body are obtained mainly through eating fruits and vegetables rich in the nutrients, or through antioxidant supplements.
Although studies suggest eating more fruits and vegetables is associated with lower risk of chronic diseases, randomized controlled trials have not shown any benefit for beta-carotene supplements, the authors note. "Therefore, carotenoids other than beta-carotene may contribute to the reduction in disease risk, and their effects on risk of disease merit investigation," the authors write.
Chaoyang Li, M.D., Ph.D., of the Centers for Disease Control and Prevention, Atlanta, and colleagues assessed the relationship between alpha-carotene and the risk of death among 15,318 adults age 20 and older who participated in the Third National Health and Nutrition Examination Survey Follow-up Study. Participants underwent a medical examination and provided blood samples between 1988 and 1994, and were followed through 2006 to determine whether and how they died.
Over the course of the study, 3,810 participants died; the risk for dying was lower with higher levels of alpha-carotene in the blood. Compared with individuals with blood alpha-carotene levels between 0 and 1 micrograms per deciliter, the risk of death during the study period was 23 percent lower among who had concentrations between 2 and 3 micrograms per deciliter, 27 percent lower with levels between 4 and 5 micrograms per deciliter, 34 percent lower with levels between 6 and 8 micrograms per deciliter and 39 percent lower with levels of 9 micrograms per deciliter or higher.
Higher alpha-carotene concentration also appeared to be associated with lower risk of dying from cardiovascular disease or cancer individually, and of all other causes. "The association between serum alpha-carotene concentrations and risk of death from all causes was significant in most subgroups stratified by demographic characteristics, lifestyle habits and health risk factors," the authors write.
Alpha-carotene is chemically similar to beta-carotene but may be more effective at inhibiting the growth of cancer cells in the brain, liver and skin, they note. "Moreover, results from a population-based case-control study of the association between the consumption of fruits and vegetables and risk of lung cancer suggest that consumption of yellow-orange (carrots, sweet potatoes or pumpkin and winter squash) and dark-green (broccoli, green beans, green peas, spinach, turnips greens, collards and leaf lettuce) vegetables, which have a high alpha-carotene content, was more strongly associated with a decreased risk of lung cancer than was consumption of all other types of vegetables," the authors write.
The results support increasing fruit and vegetable consumption as a way of preventing premature death, and suggest a need for clinical research into the health benefits of alpha-carotene, they conclude.
Oxygen-related damage to DNA, proteins and fats may play a role in the development of chronic diseases like heart disease and cancer, according to background information in the article.
Carotenoids -- including beta-carotene, alpha-carotene and lycopene -- are produced by plants and microorganisms and act as antioxidants, counteracting this damage. Carotenoids in the human body are obtained mainly through eating fruits and vegetables rich in the nutrients, or through antioxidant supplements.
Although studies suggest eating more fruits and vegetables is associated with lower risk of chronic diseases, randomized controlled trials have not shown any benefit for beta-carotene supplements, the authors note. "Therefore, carotenoids other than beta-carotene may contribute to the reduction in disease risk, and their effects on risk of disease merit investigation," the authors write.
Chaoyang Li, M.D., Ph.D., of the Centers for Disease Control and Prevention, Atlanta, and colleagues assessed the relationship between alpha-carotene and the risk of death among 15,318 adults age 20 and older who participated in the Third National Health and Nutrition Examination Survey Follow-up Study. Participants underwent a medical examination and provided blood samples between 1988 and 1994, and were followed through 2006 to determine whether and how they died.
Over the course of the study, 3,810 participants died; the risk for dying was lower with higher levels of alpha-carotene in the blood. Compared with individuals with blood alpha-carotene levels between 0 and 1 micrograms per deciliter, the risk of death during the study period was 23 percent lower among who had concentrations between 2 and 3 micrograms per deciliter, 27 percent lower with levels between 4 and 5 micrograms per deciliter, 34 percent lower with levels between 6 and 8 micrograms per deciliter and 39 percent lower with levels of 9 micrograms per deciliter or higher.
Higher alpha-carotene concentration also appeared to be associated with lower risk of dying from cardiovascular disease or cancer individually, and of all other causes. "The association between serum alpha-carotene concentrations and risk of death from all causes was significant in most subgroups stratified by demographic characteristics, lifestyle habits and health risk factors," the authors write.
Alpha-carotene is chemically similar to beta-carotene but may be more effective at inhibiting the growth of cancer cells in the brain, liver and skin, they note. "Moreover, results from a population-based case-control study of the association between the consumption of fruits and vegetables and risk of lung cancer suggest that consumption of yellow-orange (carrots, sweet potatoes or pumpkin and winter squash) and dark-green (broccoli, green beans, green peas, spinach, turnips greens, collards and leaf lettuce) vegetables, which have a high alpha-carotene content, was more strongly associated with a decreased risk of lung cancer than was consumption of all other types of vegetables," the authors write.
The results support increasing fruit and vegetable consumption as a way of preventing premature death, and suggest a need for clinical research into the health benefits of alpha-carotene, they conclude.
Sunday, November 21, 2010
I still suggest traders or investors to lighten their stock holding on the way up of this rally
The current stock market is very susceptible to news, because the lack of conviction on the part of both buyers and sellers. This leaves the daily moves in the hands of traders who bounce the indices from support to resistance in days, resulting in extended periods of range-bound trading. If the pattern continues, a solid move in either direction could be postponed until next year.
From August to November, A lot of rallies has been forced by liquidity, and once that injection of cash stops, I suspect the market's ability to launch another rally.
Jobs are still missing in this rally, housing prices are still relatively weak, earnings were better because the projection was so low, and ultimately, there's not a real big reason to buy stocks.
Ireland has formally requested substantial "financial assistance" from the European Union. The money is required to avoid the collapse of Irish banks, which have seen a major outflow of funds over the last year.
Personally, I still suggest traders or investors to lighten their stock holding on the way up of this rally.
From August to November, A lot of rallies has been forced by liquidity, and once that injection of cash stops, I suspect the market's ability to launch another rally.
Jobs are still missing in this rally, housing prices are still relatively weak, earnings were better because the projection was so low, and ultimately, there's not a real big reason to buy stocks.
Ireland has formally requested substantial "financial assistance" from the European Union. The money is required to avoid the collapse of Irish banks, which have seen a major outflow of funds over the last year.
Personally, I still suggest traders or investors to lighten their stock holding on the way up of this rally.
Saturday, November 20, 2010
Whole Grains cut Diabetes risk
Researchers from the Harvard School of Public Health investigated the diet records and blood samples of nearly 1,000 healthy middle-aged adults. They measured levels of insulin and hemoglobin A1C as well as homocysteine and cholesterol levels.
Data showed a lower risk of diabetes and heart disease in people eating a diet high in whole grains. The results were published in the American Journal of Clinical Nutrition on February 1, 2006.
Just a month ago published in the same medical journal, another group of researchers from the Tufts University released a similar finding. Scientists found that as whole grain intake increased in older adults, fasting blood sugar levels and body mass index (BMI) were lower.
Results also showed that people who consumed a high intake of refined grains had twice the risk of having diabetes and heart disease than those people who consumed the least refined grains.
Prior to these two recent studies, a few large-scale trials have already been published with the same findings. For instance, the Health Professionals Follow-up Study of 43,000 male health professionals published in September 2002 found that those who consumed the most whole grains were 42 percent less likely to develop diabetes.
Another study involving 4,300 middle-aged Finns published in March 2003 found that people eating highest amounts of whole grains were 35 percent less likely to develop diabetes.
Scientists don't know exactly which nutrients in whole grains prevent diabetes, but they generally recommended eating 3 servings daily based on the results of their studies. This recommendation is consistent with the Dietary Guidelines for Americans 2005 which recommends that all adults eat half their grains as whole grains - that's at least 3 servings of whole grains a day.
Most of the calories in grains come from carbohydrate, and carbohydrate is the type of nutrient that affects bloods glucose level the most after meals. For that reason, people with diabetes are advised to monitor their carbohydrate intake and to match the amount of carbohydrate they eat with the amount of insulin they take before meals or the amount of insulin their pancreas can secrete.
For a person with Type 2 diabetes, high blood glucose levels after a meal may indicate that the meal contained more carbohydrate than the pancreas could handle. Changes in either food choices or medication may be in order to maintain blood glucose control.
Most nutrition experts agree that including carbohydrate-containing foods such as fruits, vegetables, whole grains, legumes, and low-fat milk in a diabetes meal plan is good for both good health and effective diabetes management. Such foods are important sources of energy, fiber, vitamins, and minerals.
Choosing whole grains over refined grains may help with blood glucose control since the soluble fiber found in some grains slows digestion, and any kind of fiber helps to fill you up, so you may consume fewer calories overall.
People who include whole grains in their daily meals have been found to have a reduced risk of some chronic diseases, including heart disease and Type 2 diabetes. But even if you already have Type 2 diabetes, consuming at least three servings of whole grains daily may help you with weight management and reduce the likelihood of constipation.
For women planning a pregnancy, eating grains fortified with folic acid before as well as during pregnancy helps prevent neural tube defects in the fetus during development. Why not go with the whole grain? You and your health will only benefit.
We need to eat at least three ounces of whole grains every day, according to the 2005 “Dietary Guidelines for Americans” . They say that at least half of the grains that we eat should be whole.
Data showed a lower risk of diabetes and heart disease in people eating a diet high in whole grains. The results were published in the American Journal of Clinical Nutrition on February 1, 2006.
Just a month ago published in the same medical journal, another group of researchers from the Tufts University released a similar finding. Scientists found that as whole grain intake increased in older adults, fasting blood sugar levels and body mass index (BMI) were lower.
Results also showed that people who consumed a high intake of refined grains had twice the risk of having diabetes and heart disease than those people who consumed the least refined grains.
Prior to these two recent studies, a few large-scale trials have already been published with the same findings. For instance, the Health Professionals Follow-up Study of 43,000 male health professionals published in September 2002 found that those who consumed the most whole grains were 42 percent less likely to develop diabetes.
Another study involving 4,300 middle-aged Finns published in March 2003 found that people eating highest amounts of whole grains were 35 percent less likely to develop diabetes.
Scientists don't know exactly which nutrients in whole grains prevent diabetes, but they generally recommended eating 3 servings daily based on the results of their studies. This recommendation is consistent with the Dietary Guidelines for Americans 2005 which recommends that all adults eat half their grains as whole grains - that's at least 3 servings of whole grains a day.
Most of the calories in grains come from carbohydrate, and carbohydrate is the type of nutrient that affects bloods glucose level the most after meals. For that reason, people with diabetes are advised to monitor their carbohydrate intake and to match the amount of carbohydrate they eat with the amount of insulin they take before meals or the amount of insulin their pancreas can secrete.
For a person with Type 2 diabetes, high blood glucose levels after a meal may indicate that the meal contained more carbohydrate than the pancreas could handle. Changes in either food choices or medication may be in order to maintain blood glucose control.
Most nutrition experts agree that including carbohydrate-containing foods such as fruits, vegetables, whole grains, legumes, and low-fat milk in a diabetes meal plan is good for both good health and effective diabetes management. Such foods are important sources of energy, fiber, vitamins, and minerals.
Choosing whole grains over refined grains may help with blood glucose control since the soluble fiber found in some grains slows digestion, and any kind of fiber helps to fill you up, so you may consume fewer calories overall.
People who include whole grains in their daily meals have been found to have a reduced risk of some chronic diseases, including heart disease and Type 2 diabetes. But even if you already have Type 2 diabetes, consuming at least three servings of whole grains daily may help you with weight management and reduce the likelihood of constipation.
For women planning a pregnancy, eating grains fortified with folic acid before as well as during pregnancy helps prevent neural tube defects in the fetus during development. Why not go with the whole grain? You and your health will only benefit.
We need to eat at least three ounces of whole grains every day, according to the 2005 “Dietary Guidelines for Americans” . They say that at least half of the grains that we eat should be whole.
Tuesday, November 16, 2010
I do not expect the marke drop lower than 1130 without a significant rebound
The major indexes tumbled in a broad sell-off Tuesday, as concerns about a slowdown in China and Ireland's debt problems appeared to weigh on the market. European debt worries and China rate-hike fears slammed U.S. stocks, adding to the market's bearish trend.
Traders on Wall Street have been holding back on buying recently, as they await more clarity on the economic outlook for the United States, Europe and China.
Technically, S&P 500 may get a short term rebound at today's support 1173 or next support at 50 days moving average 1150-1160, the last sand of line will be 1130. However, I do not expect the market drop lower than 1130 without a significant rebound.
I expect the market near term sell off will pause after this week. You may want to cover some of your short positions when market hit the major supports I mention above.
Traders on Wall Street have been holding back on buying recently, as they await more clarity on the economic outlook for the United States, Europe and China.
Technically, S&P 500 may get a short term rebound at today's support 1173 or next support at 50 days moving average 1150-1160, the last sand of line will be 1130. However, I do not expect the market drop lower than 1130 without a significant rebound.
I expect the market near term sell off will pause after this week. You may want to cover some of your short positions when market hit the major supports I mention above.
Sunday, November 14, 2010
With the high bullish sentiment number, what the bears need are some bad news and catalysis to trigger the selling
The AAII Sentiment numbers were released today and showed a huge bullish jump of 9.3% to 57.6%. This is the highest bullish sentiment number since January 2007. And with Wednesday’s Investor Intelligence (II) Advisors Sentiment Survey at the highest levels since April of this year, and stocks at annual highs, it is time to go on the defensive for the short term.
Even though the sentiment numbers and our own internal indicators are very overbought, the charts of the major indices are still strong. Friday’s late rally pulled the intraday lows out of the zones identified as immediate support. Nevertheless, sentiment readings like those from AAII and II are clear warnings that something more serious may be coming.
I will be watching Europe very closely, the markets were giving a great amount of importance to the midterm elections and the Fed's new plan last two months, but now the market could face sovereign debt concerns again. With the high bullish sentiment number I mention above, what the bears need are some bad news and catalysis to trigger the selling.
Even though the sentiment numbers and our own internal indicators are very overbought, the charts of the major indices are still strong. Friday’s late rally pulled the intraday lows out of the zones identified as immediate support. Nevertheless, sentiment readings like those from AAII and II are clear warnings that something more serious may be coming.
I will be watching Europe very closely, the markets were giving a great amount of importance to the midterm elections and the Fed's new plan last two months, but now the market could face sovereign debt concerns again. With the high bullish sentiment number I mention above, what the bears need are some bad news and catalysis to trigger the selling.
Saturday, November 13, 2010
EGCG - potent extract of green tea against cancer
If you drink green tea, you are providing your body with protection against a host diseases brought about by free-radical damage. Several large studies have shown that the antioxidant effects of green tea can help lower the risk of developing cancer of the digestive system, prostate cancer, cervical cancer, and breast cancer in women.
Studies have also shown that green tea also protects against heart disease by lowering cholesterol levels and preventing the blood clots that can lead to atherosclerosis (clogged arteries).
Women experiencing hot flashes associated with menopause may find that drinking green tea morning and night may help reduce their frequency. Limited studies report that green tea helps balance estrogen levels, and which can help prevent not only hot flashes but discourage certain types of breast cancer as well.
Green tea has also been used to prevent tooth decay, increase air low to the lungs in asthma patients, and increase mental alertness (the last two effects are probably due in some part to the caffeine that is naturally found in all teas). Also, several small have shown that green tea extract (GTE) is an appetite suppressant and promotes weight loss in humans. It is now widely available in pharmacies and even some grocery stores in dietary supplements designed to help you lose weight.
Studies have also shown that green tea also protects against heart disease by lowering cholesterol levels and preventing the blood clots that can lead to atherosclerosis (clogged arteries).
Women experiencing hot flashes associated with menopause may find that drinking green tea morning and night may help reduce their frequency. Limited studies report that green tea helps balance estrogen levels, and which can help prevent not only hot flashes but discourage certain types of breast cancer as well.
Green tea has also been used to prevent tooth decay, increase air low to the lungs in asthma patients, and increase mental alertness (the last two effects are probably due in some part to the caffeine that is naturally found in all teas). Also, several small have shown that green tea extract (GTE) is an appetite suppressant and promotes weight loss in humans. It is now widely available in pharmacies and even some grocery stores in dietary supplements designed to help you lose weight.
The cancer-protective effects of green tea have been reported in several population-based studies. For example, cancer rates tend to be low in countries such as Japan where green tea is regularly consumed. However, it is not possible to determine from these population-based studies whether green tea actually prevents cancer in people. Emerging animal and clinical studies are beginning to suggest that EGCG may play an important role in the prevention of cancer.
It has been suggested that EGCG and other tea catechins suppress tumor promotion by inhibiting the release of tumor necrosis factor-alpha, which is believed to stimulate tumor promotion and progression of initiated cells as well as premalignant cells. Furthermore, EGCG was shown to reduce specific binding of both the 12-Otetradecanoylphorbol-13-acetate (TPA)-type and the okadaic acid-type tumor promoters (the two major classes of tumor-promoting agents) to their receptors. This "sealing" effect of EGCG is achieved by its interaction with the phospholipid bilayer of the cell membrane.
When non-Hodgkin's lymphoma cells were transplanted into mice, green tea prevented 50% of the tumors from taking hold and significantly inhibited growth of the tumors.
Bladder cancer
A few studies have examined the relationship between bladder cancer and green tea consumption. In one study that compared people with and without bladder cancer, researchers found that women who drank black tea and powdered green tea were less likely to develop bladder cancer. A follow-up study by the same group of researchers revealed that bladder cancer patients (particularly men) who drank green tea had a substantially better 5-year survival rate than those who did not.
Breast cancer
Studies suggest that EGCG inhibits the growth of breast cancer cells, both in live animals and test tubes.
A Japanese study comparing 472 women with breast cancer who drank differing amounts of green tea indicates that EGCG may decrease both the severity of the initial diagnosis and the likelihood of recurrence. The researchers found that the women with Stage I, II and III breast cancers that drank five or more cups of green tea per day were less likely to have cancer that spread to the nymph nodes. In addition, the greater consumption of green tea by women with Stage I or II breast cancer was associated with lower incidence of recurrence. No correlation was shown with women who had Stage III cancers. Another Japanese study showed less overall incidence of cancer among 8,000 people who drank ten or more cups of green tea a day.
Colorectal cancer
A study at the Linus Pauling Institute at Oregon State University on mice that were genetically predisposed to develop tumors in their intestines revealed after 12 weeks of treatment that mice that were given green tea had significantly fewer tumors than mice that received no treatment (Carcinogenesis, February 2003).
Phenol sulsotransferases are involved in cancer growth, and EGCG was shown to inhibit this activity in a human colon cancer call line (Biol Pharm Bull 2000 Jun;23(6):695-9).
Chinese scientists discovered that EGCG inhibits angiogenesis (the production of new blood vessels) in mice inoculated with human colon cancer. This blocking of new blood vessel growth may be an important part of the overall anti-cancer action of polyphenols, since it impedes tumor growth.
Esophageal cancer Studies in laboratory animals have found that green tea polyphenols inhibit the growth of esophageal cancer cells. However, results of studies in people have been conflicting. In fact, some evidence suggests the hotter the tea (or any other hot beverage), the greater the risk of developing esophageal cancer. However, researchers reporting on a case-control study, found that Chinese men and women who drink green tea have a reduced risk of up to 60 percent of developing esophageal cancer (Journal of the National Cancer Institute, June 1, 1994).
Esophageal cancer Studies in laboratory animals have found that green tea polyphenols inhibit the growth of esophageal cancer cells. However, results of studies in people have been conflicting. In fact, some evidence suggests the hotter the tea (or any other hot beverage), the greater the risk of developing esophageal cancer. However, researchers reporting on a case-control study, found that Chinese men and women who drink green tea have a reduced risk of up to 60 percent of developing esophageal cancer (Journal of the National Cancer Institute, June 1, 1994).
Lung cancer
Consumption of green tea was found to be associated with a reduced risk of lung cancer among non-smokers but not among smokers. Also among non-smokers, the risks of lung cancer decreased with increasing tea consumption. (Epidemiology 2001 Nov; 12(6):695-700).
Treatment of human lung cancer cell line A549 cells with EGCG significantly inhibited the expression levels of hnRNP B1 mRNA and the elevated levels of hnRNP B1 protein, both of which are constitutively elevated in cancer cells. Furthermore, both EGCG inhibited the promoter activity of hnRNP A2/B1 gene expression, preventing lung cancer (International Journal of Onclology 20: 1233-1239, 2002).
Pancreatic cancer
Researchers in Japan determined whether EGCG affects proliferative and invasive activity of human pancreatic carcinoma cells. The results indicate that the growth of all three pancreatic carcinoma cells (PANC-1, MIA PaCa-2 and BxPC-3) was significantly suppressed by EGCG treatment in a dose-dependent manner. EGCG may be a potent biologic inhibitor of pancreatic carcinoma, reducing their proliferative and invasive activity (Pancreas, July 2002).
Prostate cancer
In my opinion, EGCG is the most important component of green tea to the prostate cancer patient. The first evidence of its ability to induce prostate cancer apoptosis (programmed cell death) was published in Cancer Letters back in 1998 (130(1-2):1-7 1998 Aug 14).
Its pharmacologic activity extends beyond its action as an anti-oxidant. EGCG acts against urokinase, an enzyme often found in large amounts in human cancers, inhibits ornithine decarboxylase (a rate-limiting enzyme closely associated with tumor promotion), and blocks type 1 5-alpha reductase (5AR). Inhibitors of 5AR may be effective in the treatment of 5 alpha dihydrotestosterone-dependent abnormalities, such as benign prostate hyperplasia, prostate cancer, and certain skin diseases.
Urokinase breaks down the basement membrane of cell junctions which may be a key step in the process of tumor cell metastasis as well as tumor growth. EGCG attaches to urokinase and prevents these actions.
EGCG was shown to inhibit growth and induce regression of human prostate and breast cancers in athymic mice (Liao S, Umekita Y, Guo J et al. Growth inhibition and regression of human prostate and breast tumors in athymic mice by tea epigallocatechin gallate (Cancer Letters 96:239-243, 1995).
Skin cancer
Studies suggest that EGCG and green tea polyphenols have anti-inflammatory and anti-cancer properties that may help prevent the onset and growth of skin tumors. Topical application of EGCG may prevent UV-B-induced immunosuppression and precancerous cell changes after UV-B exposure (J Leukoc Biol. 2001;69:719-726).
Stomach cancer
Laboratory studies have found that green tea polyphenols inhibit the growth of stomach cancer cells in test tubes. The exposure of human stomach cancer KATO III cells to EGCG led to both growth inhibition and the induction of programmed cell death (apoptosis)
Wednesday, November 10, 2010
The short and medium term momentum of the market is still in bullish mode, there is no way for swing traders to short this market successfully until the major support of 1080 or 1030 is broken
The S&P 500 Index rested on its 10-day trendline as an intraday springboard, erasing an early deficit to finish 5.3 points, closed at 1218.71.
As I said on last post that the S&P 500 will test the 10 days moving average at 1200. Today's low is at current 10 days moving average 1204, a reversal that takes the S&P through its major support at 1200. you should cover your short today at 1204 which started two days ago.
Some of you may use this pullback as the buying opportunity that you had hoped for. The favorite groups are still technology and precious metals stocks. But manufacturing and solid dividend-paying blue chips should also be on the list for buyers of quality issue. I suspect stocks will stay in a range, largely directionless, leading into the weekend
The Fed did QE1 and there was no tangible results, so now they are doing QE2 which seems to be an act of desperation, because they wouldn't be doing it unless the reality was more negative than we are aware of after the QE1. The Fed continues to manipulate the equity market higher, push the USD down, which in turn sends stocks and commodities sharply higher. The market is extremely extended, but it can remain that way longer than most of the investors think.
The majority of investors appears to be in almost total denial mode about the economic depression start from 2008. They seems to believe that this market has already found the bottom, so it will be a tough road the next two years, I expect another significant down market cycle starting sometime in 2011. However, the short and medium term momentum of the market is still in bullish mode. Most of the short term investors are still riding this bull-express train. There is no way for swing traders to short this market successfully until the major support of 1080 or 1030 is broken.
As I said on last post that the S&P 500 will test the 10 days moving average at 1200. Today's low is at current 10 days moving average 1204, a reversal that takes the S&P through its major support at 1200. you should cover your short today at 1204 which started two days ago.
Some of you may use this pullback as the buying opportunity that you had hoped for. The favorite groups are still technology and precious metals stocks. But manufacturing and solid dividend-paying blue chips should also be on the list for buyers of quality issue. I suspect stocks will stay in a range, largely directionless, leading into the weekend
The Fed did QE1 and there was no tangible results, so now they are doing QE2 which seems to be an act of desperation, because they wouldn't be doing it unless the reality was more negative than we are aware of after the QE1. The Fed continues to manipulate the equity market higher, push the USD down, which in turn sends stocks and commodities sharply higher. The market is extremely extended, but it can remain that way longer than most of the investors think.
The majority of investors appears to be in almost total denial mode about the economic depression start from 2008. They seems to believe that this market has already found the bottom, so it will be a tough road the next two years, I expect another significant down market cycle starting sometime in 2011. However, the short and medium term momentum of the market is still in bullish mode. Most of the short term investors are still riding this bull-express train. There is no way for swing traders to short this market successfully until the major support of 1080 or 1030 is broken.
Sunday, November 7, 2010
Short this overbought market, target is 10 days moving average 1194-1200.
All three of the major market indexes are at year-to-date highs and at levels not seen since September 2008.
At this overbought level, you should take the profit and wait for another opportunity. I will not long this market unless there is 3% to 5% correction and a resume rally shortly after.
If you want to short this overbought market, you should have done that on last Friday because the 2 day RSI on most of the indices are over 99. It may take 2 to 3 days to digest this overbought situation. Target is 10 days moving average 1194-1200. S&P500 closed at 1125.85 on Friday, there will be 25-30 points profit if it hit 1194-1200 in the next few days.
However, patient investors may want to wait one more week before shorting this market because the momentum still on the way up. Your successful rate will be higher if the market is on the way down instead.
At this overbought level, you should take the profit and wait for another opportunity. I will not long this market unless there is 3% to 5% correction and a resume rally shortly after.
If you want to short this overbought market, you should have done that on last Friday because the 2 day RSI on most of the indices are over 99. It may take 2 to 3 days to digest this overbought situation. Target is 10 days moving average 1194-1200. S&P500 closed at 1125.85 on Friday, there will be 25-30 points profit if it hit 1194-1200 in the next few days.
However, patient investors may want to wait one more week before shorting this market because the momentum still on the way up. Your successful rate will be higher if the market is on the way down instead.
Saturday, November 6, 2010
For a Healthy Heart, Don’t Skip Breakfast!
Prior research suggests that breakfast eaters may be healthier than people who skip breakfast, and now a study in the American Journal of Clinical Nutrition suggests a nutritious breakfast may be especially good for your heart. Specifically, the recent study shows that regular breakfast eaters may reduce risk factors linked to heart disease.
While prior research has shown that skipping breakfast may lower a person’s energy level and increase the risk of weight gain, less is known about the effects of skipping breakfast on other body organs and functions.
In this study, 2,184 participants, 9 to 15 years old, initially filled out a questionnaire about diet and physical activity and stated whether they usually ate breakfast before school or not. Twenty years later, one third of the original participants filled out a meal frequency questionnaire, had their waist size measured, and had blood levels of triglycerides, total and LDL (“bad”) cholesterol, and fasting insulin (insulin levels after no food has been eaten overnight) checked. Participants were then classified into four groups:
• skipped breakfast in neither childhood nor adulthood,
• skipped breakfast only in childhood,
• skipped breakfast only in adulthood, or
• skipped breakfast in both childhood and adulthood.
Results showed that people who skipped breakfast in both childhood and adulthood had a larger waist size and total cholesterol and LDL cholesterol levels compared with people who ate breakfast in both childhood and adulthood. They also had higher fasting insulin levels, which indicates they have insulin resistance, a risk factor for diabetes and heart disease.
Breakfast skippers also tended to be single, have a lower education level, and were more likely to smoke, watch TV, get less physical activity, and have a less healthy diet compared with breakfast eaters.
The authors comment, “Skipping breakfast was associated with a larger waist circumference, cardiometabolic risk factors, poorer diet quality, and unhealthy lifestyle behaviors.” They add that promoting the benefits of eating breakfast may be an important public health message.
More reasons to be a breakfast eater
There are many good reasons to eat breakfast, and prior research has shown that compared with breakfast skippers, breakfast eaters tend to have:
• Better habits. People who eat breakfast tend to have healthier diets and get more physical activity.
• A more nutritious diet. Breakfast eaters tend to eat less daily fat and cholesterol and more fiber, vitamins, and minerals.
• A healthier weight. Some studies suggest that breakfast eaters have a lower weight compared with breakfast skippers
Friday, November 5, 2010
55 Facts About Blood
- 4.5 million Americans will a need blood transfusion each year.
- 43,000 pints: amount of donated blood used each day in the U.S. and Canada.
- Someone needs blood every two seconds.
- Only 37 percent of the U.S. population is eligible to donate blood – less than 10 percent do annually.**
- About 1 in 7 people entering a hospital need blood.
- One pint of blood can save up to three lives.
- Healthy adults who are at least 17 years old, and at least 110 pounds may donate about a pint of blood – the most common form of donation – every 56 days, or every two months. Females receive 53 percent of blood transfusions; males receive 47 percent.
- 94 percent of blood donors are registered voters.
- Four main red blood cell types: A, B, AB and O. Each can be positive or negative for the Rh factor. AB is the universal recipient; O negative is the universal donor of red blood cells.
- Dr. Karl Landsteiner first identified the major human blood groups – A, B, AB and O – in 1901.
- One unit of blood can be separated into several components: red blood cells, plasma, platelets and cryoprecipitate.
- Red blood cells carry oxygen to the body's organs and tissues.
- Red blood cells live about 120 days in the circulatory system.
- Platelets promote blood clotting and give those with leukemia and other cancers a chance to live.
- Plasma is a pale yellow mixture of water, proteins and salts.
- Plasma, which is 90 percent water, makes up 55 percent of blood volume.
- Healthy bone marrow makes a constant supply of red cells, plasma and platelets.
- Blood or plasma that comes from people who have been paid for it cannot be used to human transfusion.
- Granulocytes, a type of white blood cell, roll along blood vessel walls in search of bacteria to engulf and destroy.
- White cells are the body's primary defense against infection.
- Apheresis is a special kind of blood donation that allows a donor to give specific blood components, such as platelets.
- Forty-two days: how long most donated red blood cells can be stored.
- Five days: how long most donated platelets can be stored.
- One year: how long frozen plasma can be stored.
- Much of today's medical care depends on a steady supply of blood from healthy donors.
- 3 pints: the average whole blood and red blood cell transfusion.*
- Children being treated for cancer, premature infants and children having heart surgery need blood and platelets from donors of all types, especially type O.
- Anemic patients need blood transfusions to increase their red blood cell levels.
- Cancer, transplant and trauma patients, and patients undergoing open-heart surgery may require platelet transfusions to survive.
- Sickle cell disease is an inherited disease that affects more than 80,000 people in the United States, 98 percent of whom are of African descent.
- Many patients with severe sickle cell disease receive blood transfusions every month.
- A patient could be forced to pass up a lifesaving organ, if compatible blood is not available to support the transplant.
- Thirteen tests (11 for infectious diseases) are performed on each unit of donated blood.
- 17 percent of non-donors cite "never thought about it" as the main reason for not giving, while 15 percent say they're too busy.
- The #1 reason blood donors say they give is because they "want to help others."
- Shortages of all blood types happen during the summer and winter holidays.
- Blood centers often run short of types O and B red blood cells.
- The rarest blood type is the one not on the shelf when it's needed by a patient.
- There is no substitute for human blood.
- If all blood donors gave three times a year, blood shortages would be a rare event (The current average is about two.).
- If only one more percent of all Americans would give blood, blood shortages would disappear for the foreseeable future.
- 46.5 gallons: amount of blood you could donate if you begin at age 17 and donate every 56 days until you reach 79 years old.
- Four easy steps to donate blood: medical history, quick physical, donation and snacks.
- The actual blood donation usually takes about 10 minutes. The entire process – from the time you sign in to the time you leave – takes about an hour.
- After donating blood, you replace the fluid in hours and the red blood cells within four weeks. It takes eight weeks to restore the iron lost after donating.
- You cannot get AIDS or any other infectious disease by donating blood.
- 10 pints: amount of blood in the body of an average adult.
- One unit of whole blood is roughly the equivalent of one pint.
- Blood makes up about 7 percent of your body's weight.
- A newborn baby has about one cup of blood in his body.
- Giving blood will not decrease your strength.
- Any company, community organization, place of worship or individual may contact their local community blood center to host a blood drive.
- Blood drives hosted by companies, schools, places of worship and civic organizations supply roughly half of all blood donations across the U.S.
- People who donate blood are volunteers and are not paid for their donation.
- 500,000: the number of Americans who donated blood in the days following the September 11 attacks.
Thursday, November 4, 2010
Timing and confirmation is essential to short the current market with such a extreme bullish momentum
The S&P 500 Index settled at a two-year peak, adding 23.1 points at 1121.06 by the close. What's more, today marks the broad-marke finish north of the 1200 level since May 2010.
The Fed’s plan to buy $600 billion in bonds in an effort to drive down interest rates and induce more lending, this let the investors have optimism that the global economy would not worsen and corporate profits would increase. However, the Fed can’t on its own resolve all of the country’s economic troubles. We still have a lot of uncertainty in this market.
Technically, today we reach S&P 1220 eventually, market is extremely overbought, its the time we should think about shorting this market. I still waiting for the big sell off day with high volume combine with bearish candlestick signal. Timing and confirmation is essential to short the current market with such a extreme bullish momentum.
The Fed’s plan to buy $600 billion in bonds in an effort to drive down interest rates and induce more lending, this let the investors have optimism that the global economy would not worsen and corporate profits would increase. However, the Fed can’t on its own resolve all of the country’s economic troubles. We still have a lot of uncertainty in this market.
Technically, today we reach S&P 1220 eventually, market is extremely overbought, its the time we should think about shorting this market. I still waiting for the big sell off day with high volume combine with bearish candlestick signal. Timing and confirmation is essential to short the current market with such a extreme bullish momentum.
Tuesday, November 2, 2010
The risk reward ratio is definitely favor the bears base on the 1200-1220 resistances and the current overbought market
The market seems to have high hopes for the outcome of this week's key events, as stocks shot higher right out of the gate this morning.
The S&P 500 Index add 9.2 points, closed at 1193.57 to mark its best daily close since May. However, the SPX is at potential pressure zone in the 1200 region. 200 weeks moving average is at 1193.12 , 80 months moving average is right above 1200. April high is at 1220.
In the meantime, the risk reward ratio is definitely favor the bears base on the 1200-1220 resistances mention above and the current overbought market. However, the momentum is still up, timing is everything. I will not suggest to short the market right now.(short the market on the way up), instead I will wait for the first significant down day and the candlestick sell signal for confirmation before enter any short position. (short it on the way down)
The S&P 500 Index add 9.2 points, closed at 1193.57 to mark its best daily close since May. However, the SPX is at potential pressure zone in the 1200 region. 200 weeks moving average is at 1193.12 , 80 months moving average is right above 1200. April high is at 1220.
In the meantime, the risk reward ratio is definitely favor the bears base on the 1200-1220 resistances mention above and the current overbought market. However, the momentum is still up, timing is everything. I will not suggest to short the market right now.(short the market on the way up), instead I will wait for the first significant down day and the candlestick sell signal for confirmation before enter any short position. (short it on the way down)
Monday, November 1, 2010
There is certainly enough news this week to create either a breakout or a breakdown
Stock market had strength in the early morning trading near its five-month high, but the mix of a stronger dollar, technical resistance, and uncertainty ahead of this week's major events left stocks to slide and nearly finish with a loss. S&P500 was up 1.12 points, closed at 1184.38.
In addition to the elections and the Fed meeting, the monthly jobs numbers will be released before the opening on Friday. There is certainly enough news this week to create either a breakout or a breakdown. The best thing to do is to wait until the the next buying panic combine with extreme overbought signal which will force all the bears to surrender, then you may start to short this market.
In addition to the elections and the Fed meeting, the monthly jobs numbers will be released before the opening on Friday. There is certainly enough news this week to create either a breakout or a breakdown. The best thing to do is to wait until the the next buying panic combine with extreme overbought signal which will force all the bears to surrender, then you may start to short this market.
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