In our body, the activity of blood is not spontaneous, it's rely on different organs of the body to do the job. The flow of blood is the result of the heart contraction and expansion, resulting pressures; blood in the left ventricle is pumped out under pressure, to the aorta, then the pressure continues to be maintained and promote, this is the aortic blood pressure, commonly known as systolic blood pressure . Thereafter, the heart with diastolic blood flow into the right atrium, we call it diastolic blood pressure.
Human body's blood pressure, mainly come from contraction and release of the heart, but in order to cope with various changes, there must be "fine tuning" mechanism. One of them is the blood vessel. Vascular wall of smooth muscle, the muscle can contract and expand. If it contract the blood pressure will rise; if it expand the blood pressure will decrease.
In the contraction, there is a set of actions, movements began in the liver. Liver first to create "angiotensinogen" (Angiotensinogen) hormone. This hormone then travel to kidneys with blood, from renin to "angiotensin-1" (Angiotensin-I, ANGI); ANGI go further with the blood to the lungs, from there, a biological enzyme called ACE change it to "vascular tone factor 2 "(Angiotensin-II,ANGII). ANGII will stick to blood vessels receptor (called AT1 Receptor), and the smooth muscle of vessel walls in blood vessels will narrow, as a result blood pressure will increase correspondingly.
A drug called Captopril, can greatly inhibit the ACE, thus reducing blood pressure, especially Systolic Pressure. However, there is an undesirable side effect of Captopril, it cause constantly dry cough. Another class of antihypertensive drugs, such as Losartan, its function is to prevent the ANGII sticking to the AT1 Receptor, and thus allow increased blood pressure. Losartan do not cause the coughing side effects, gradually becoming more popular blood pressure medicine; but the result of lowering blood pressure was unsatisfactory, because it's role is mainly in blood vessels, the blood will wash it off easily.
However, heart is not the only organ can regulate the blood pressure. Other body tissues, such as blood vessel itself, would be useful. Vascular wall smooth muscle contract, blood pressure goes up; on the contrary, with the smooth muscle relax, blood pressure will go down, also the narrower the blood vessels the higher the blood pressure. There are many factors that can affect the level of blood pressure. Such as height, blood viscosity. The higher the body, the heart requires more pressure to pump blood to the body; if the blood is viscous, the heart have to pump harder and the blood pressure will be higher. Other factors include the mental state, the pace of life, eating habits, and even weather.
Why we must pay attention to blood pressure? Because in normal circumstances, we rely on healthy blood pressure , it is very significant that blood can transport around our body, if blood pressure is too low, there is no blood supply to the body, on the contrary, blood pressure is too high, blood vessel will damage. According to WHO guidelines issued in 1999, 120/ 80 upper and lower pressure is the ideal ratio; 139/ 89 is normal blood pressure, 140/ 90 to 160/ 95 is high blood pressure 161/ 96 would be very high blood pressure.
Dietary supplement and natural food supplement is ideal in treating high blood pressure. Scientists pointed out that resveratrol from grape Resveratrol, may reduce the blood vessel AT1. On the other hand, Quercetin can on its own, reducing the pressure. There is also a good thing, called arginine. Under normal condtions, vascular wall cells themselves have the ability to reduce blood pressure, it is arginine, with its manufacture of nitric oxide (NO); after NO stimulate a biological enzyme called Guanylate Cyclase, it turn into a substance called CGMP, which can relax smooth muscle of blood vessel walls, as well as blood vessels, blood pressure will drop thereafter. Arginine is the raw materials to make NO in vascular endothelial cell.
Therefore, a combination supplement and health formula of resveratrol, Quercetin and Arginine, can be a subtle way to help reduce blood pressure, maintain healthy blood vessel.
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